Fundamentals Of Pharmacology VitalSource eBook (6e)

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Fundamentals of Pharmacology 6e presents key scientific and clinical principles to facilitate a greater understanding of pharmacology.  This wholly Australasian text provides comprehensive and current coverage of topics, written in a clear style with a reader-friendly design.  The sixth edition is still the only completely Australasian text written for Australian and New Zealand students studying pharmacology.

Preface
Acknowledgments
Visual Guide
Figures
Tables

SECTION I PHARMACOLOGY WITHIN THE SOCIAL CONTEXT

chapter 1 A Historical Perspective
chapter 2 Sociocultural Aspects

SECTION II PHARMACOLOGY WITHIN THE PROFESSIONAL CONTEXT

chapter 3 Nurses and the Law
chapter 4 Ethical Issues
chapter 5 The Role and Responsibilities of Nurses
chapter 6 The Roles and Responsibilities of Other Health Care Professionals

SECTION III DRUG ADMINISTRATION AND PROFESSIONAL RESPONSIBILITIES

chapter 7 Drug Formulations, Storage and Routes of Administration
chapter 8 The Clinical Decision-Making Process
chapter 9 Drug Administration Strategies and Documentation
chapter 10 Medication Errors
chapter 11 Management of Common Adverse Drug Reactions
chapter 12 Risk Communication: Balancing the Benefits and Risks of Drug Treatment

SECTION IV GENERAL ASPECTS OF PHARMACOLOGY

chapter 13 Drug Nomenclature
chapter 14 Pharmacokinetics: Absorption and Distribution
chapter 15 Pharmacokinetics: Metabolism and Excretion
chapter 16 Drug Interactions
chapter 17 Pharmacodynamics
chapter 18 Drug Development, Evaluation and Safety
chapter 19 Pharmacogenetics
chapter 20 Pharmacokinetic Factors that Modify Drug Action
chapter 21 Paediatric and Geriatric Pharmacology

SECTION V TOXICOLOGY

chapter 22 Poisoning and Envenomation
chapter 23 The Management of Acute Clinical Overdose
chapter 24 Contemporary Drugs of Abuse
chapter 25 Drug Abuse in Sport

SECTION VI AUTONOMIC PHARMACOLOGY

chapter 26 General Aspects of Neuropharmacology
chapter 27 Adrenergic Pharmacology
chapter 28 Cholinergic Pharmacology

SECTION VII CHEMICAL MEDIATORS

chapter 29 An Introduction to Chemical Mediators
chapter 30 Histamine and Antihistamines
chapter 31 Prostaglandins and Serotonin
chapter 32 Nitric Oxide and the Endothelins

SECTION VIII THE MODULATION OF BEHAVIOUR, COGNITION AND MOTOR ACTIVITY

chapter 33 General Concepts of Psychopharmacology
chapter 34 Antipsychotic Drugs
chapter 35 Anxiolytics and Hypnotics
chapter 36 Antidepressants and Mood Stabilisers
chapter 37 Drugs Used in Neurodegenerative Disorders
chapter 38 Antiseizure Drugs and Muscle Relaxants
chapter 39 Central Nervous System Stimulants

SECTION IX DRUGS USED TO RELIEVE PAIN AND PRODUCE ANAESTHESIA

chapter 40 Narcotic Analgesics
chapter 41 Non-Steroidal Anti-Inflammatory, Antipyretic and Analgesic Drugs
chapter 42 Drugs Used to Treat Migraine
chapter 43 General Anaesthesia
chapter 44 Local Anaesthesia

SECTION X THE MODULATION OF OXYGENATION AND PERFUSION

chapter 45 Drugs Used to Lower Blood Lipids
chapter 46 Antihypertensive Drugs
chapter 47 Drugs Used to Promote Tissue Perfusion
chapter 48 Anticoagulants, Thrombolytics and Antiplatelet Drugs
chapter 49 Diuretics and Other Renal Drugs
chapter 50 Drugs Used to Treat Heart Failure
chapter 51 Drugs Used to Treat Dysrhythmias
chapter 52 Fluid and Potassium Imbalances
chapter 53 Antianaemic Drugs
chapter 54 Drugs Used to Maintain Gas Exchange
chapter 55 Over-the-Counter Respiratory Medicines

SECTION XI THE MODULATION OF GASTROINTESTINAL FUNCTION

chapter 56 Upper Gastrointestinal Tract Drugs
chapter 57 Lower Gastrointestinal Tract Drugs
chapter 58 Antiemetic Drugs

SECTION XII THE MODULATION OF BODY GROWTH, DEVELOPMENT AND METABOLISM

chapter 59 Drugs and the Pituitary Gland
chapter 60 Drugs and the Thyroid
chapter 61 Drugs and the Pancreas
chapter 62 Drugs and the Adrenal Cortex
chapter 63 Drugs and the Gonads
chapter 64 Drugs and Bone Metabolism
chapter 65 Hyperuricaemia and Gout
chapter 66 Obesity and its Treatment

SECTION XIII NUTRITIONAL AND NATURAL THERAPIES

chapter 67 Vitamins, Minerals and Amino Acids
chapter 68 Enteral and Parenteral Nutrition
chapter 69 Herbal Medicines

SECTION XIV THE MODULATION OF CELLULAR GROWTH AND PROLIFERATION

chapter 70 Introduction to Chemotherapy
chapter 71 Sulphonamides and Trimethoprim
chapter 72 Antibacterial Drugs
chapter 73 Antituberculotics and Antileprotic Drugs
chapter 74 Antiseptics and Disinfectants
chapter 75 Antiparasitic Drugs
chapter 76 Antimalarial Drugs
chapter 77 Antiviral Drugs
chapter 78 Antifungal Drugs
chapter 79 Immunomodulating Drugs
chapter 80 Cytotoxic Drugs
chapter 81 Gene Therapies

SECTION XV DRUGS USED TOPICALLY

chapter 82 Drugs Used in Diseases of the Skin
chapter 83 Drugs and the Eye

appendix A Common prescription terminology
appendix B Common American generic drug names
appendix C SI units
appendix D Drug calculations
appendix E Common symbols used in medication charts
appendix F Common word mix-ups
appendix G Drug–herbal interactions
appendix H Orphan drugs

Glossary
Index

• Update to the availability of all drugs, with newly available ones having been added, as well as those that are no longer available in Australia and New Zealand since the last edition.
• A number of chapters have been reorganised and some topics expanded considerably. The result is two new chapters: Drugs Used in the Treatment of Migraine (chapter 42) and Drugs and Bone Metabolism (chapter 64).
• Three existing chapters have been split for improved readability. Drugs Used to Treat Cardiac Insufficiency has been divided into two new chapters, Drugs Used to Treat Heart Failure (chapter 50) and Drugs Used to Treat Dysrhythmia (chapter 51). The Thyroid and Pancreas chapter has been separated into Drugs and the Thyroid (chapter 60) and Drugs and the Pancreas (chapter 61). The Adrenal Cortex and Gonads chapter has been split up into Drugs and the Adrenal Cortex (chapter 62) and Drugs and the Gonads (chapter 63).
• The separate chapters on Vitamins, Minerals and Amino Acids have been merged into one chapter called Vitamins, Minerals and Amino Acids (chapter 67).
• The therapeutic approaches associated with the management of important clinical conditions such as heart failure, hypertension, diabetes mellitus, depression, rheumatoid arthritis, asthma and pain have been brought up to date with current clinical guidelines.
• More Figures and Tables have been included to assist students in visualising difficult pharmacological concepts, the sites of actions of drugs and the range of drug effects expected in a person when particular drug groups are administered.
• All end-of-chapter questions have been reviewed. There are now over 800 end of chapter questions to assist in the consolidation of learning and a total of 77 Integrated Case Studies found in the end of Sections.
• An improved media package in MyHealthProfessionsKit website.
• Updated instructor supplements package.

• Comprehensive coverage of pharmacology for the needs of nursing and health science students
• Wholly Australasian text developed over many years to reflect the clinical environment
• Clear explanations and appropriate writing style
• A successful blend of theory and practice
• Logical structure that includes the social and professional context, principles of pharmacology and drug groups. The latter integrates pharmacological effects, their action on physiological processes and pathophysiology in order to promote conceptual understanding
• Integration of the clinical decision-making framework and a strong emphasis upon clinical applications that is reflective of the diverse range of health care settings
• Drug Summary Tables that act as a quick reference tool and succinct chapter summary. This includes generic names, trade names and special considerations
• Clinical Management Tables provide a step-by-step guide
• Strong pedagogy with liberal use of Tables, Figures, chapter salient points and end-of-chapter questions
• A variety of case scenarios that put the clinical material into context
• Instructor supplements including
  • Digital Media Archive: all figures, tables, diagrams and Drug Summary Tables in digital form for easy customisation and exportation for your teaching needs
  • Instructor Test Bank: a multiple choice test bank for all of your online or traditional assessment needs.
  • Video Segments: selected video segments with accompanying questions reflecting Australasian clinical setting.
• NEW MyHealthProfessionsKit website provides students with a completely interactive experience, bringing to life the concepts they cover in the textbook. Each student will have access to the following resources within MyHealthProfessionsKit:
  • eText complete with full search functionality, pop-glossary, and the ability to bookmark and make notes
  • Chapter-based multiple choice questions with links to the eText
  • Interactive ‘drag and drop’ revision activities
  • Animations featuring the mechanisms in action for various drugs
  • Glossary Flashcards to assist with comprehension of key terms from the text

Associate Professor Shane Bullock, Faculty of Medicine, Nursing and Health Sciences, Monash University, has published a number of articles in peer-reviewed journals in the area of nurses knowledge of pharmacology and the development of computer-assisted learning packages for nursing students.

Associate Professor Elizabeth Manias is a registered nurse and pharmacist, and is an Associate Professor at The University of Melbourne.  She has taught undergraduate and postgraduate students in the area of pharmacology and medication management issues. Her research endeavours have made a sustained contribution to medication safety, interpersonal and organisational communication and consumer participation.  Specifically, her work has examined the complex communication processes about how medications are used.  Aside from the Fundamentals of Pharmacology textbook, Dr. Manias has published her work extensively in international, peer reviewed journals.